|
|
S-adenosyl-L-methionine + paraxanthine <=> H+ + Caffeine + S-adenosyl-L-homocysteine
|
2.1.1.159
theobromine synthase
2.1.1.160
caffeine synthase
|
–
–
|
MK
|
| |
BRENDA:
BR48815
KEGG:
R07921
MetaCyc:
RXN-7601
SABIO-RK:
14236
|
|
|
|
paraxanthine + NADPH + O2 + H+ <=> 7-methylxanthine + NADP+ + formaldehyde + H2O
|
1.14.13.128
7-methylxanthine demethylase
1.14.13.178
methylxanthine N1-demethylase
|
–
–
|
BMK
|
| |
BRENDA:
BR50579
KEGG:
R07958
MetaCyc:
RXN-11517
|
|
|
|
paraxanthine + NADH + O2 + H+ <=> 7-methylxanthine + NAD+ + formaldehyde + H2O
|
1.14.13.128
7-methylxanthine demethylase
1.14.13.178
methylxanthine N1-demethylase
|
–
–
|
K
|
| |
BRENDA:
BR50579-a
KEGG:
R07957
MetaCyc:
RXN-11517_WOP
|
|
|
|
paraxanthine + O2 + H2O <=> 1,7-dimethyluric_acid + H2O2
|
1.17.3.2
xanthine oxidase
|
–
|
MK
|
| |
BRENDA:
BS375516
KEGG:
R07977
MetaCyc:
RXN-11520
|
|
|
|
Caffeine + NADH + O2 + H+ <=> paraxanthine + NAD+ + formaldehyde + H2O
|
1.14.13.128
7-methylxanthine demethylase
1.14.13.179
methylxanthine N3-demethylase
|
–
–
|
K
|
| |
BRENDA:
BS411830
KEGG:
R07954
MetaCyc:
RXN-13106_WOP
|
|
|
|
Caffeine + NADPH + O2 + H+ <=> paraxanthine + NADP+ + formaldehyde + H2O
|
1.14.13.128
7-methylxanthine demethylase
1.14.13.179
methylxanthine N3-demethylase
1.14.14.1
unspecific monooxygenase
|
–
–
–
|
MK
|
| |
BRENDA:
BS417832
KEGG:
R07939
MetaCyc:
RXN-13106
|
|
|
|
S-adenosyl-L-methionine + 7-methylxanthine <=> H+ + paraxanthine + S-adenosyl-L-homocysteine
|
not assigned
|
–
|
MK
|
| |
KEGG:
R07922
MetaCyc:
RXN-7600
|
|
|
|
paraxanthine <=> 5-Acetylamino-6-formylamino-3-methyluracil
|
2.3.1.5
arylamine N-acetyltransferase
|
–
|
K
|
| |
KEGG:
R07940
|
|
|
|
paraxanthine <=> 1-Methylxanthine
|
1.14.14.1
unspecific monooxygenase
|
–
|
K
|
| |
KEGG:
R07943
|
|
|
|
paraxanthine <=> 1,7-dimethyluric_acid
|
1.14.13
1.14.14.1
unspecific monooxygenase
|
–
–
|
K
|
| |
KEGG:
R07945
|
|
|
|
paraxanthine + NADH + H+ + O2 <=> 1-Methylxanthine + NAD+ + formaldehyde + H2O
|
1.13.12
|
–
|
K
|
| |
KEGG:
R07959
|
|
|
|
paraxanthine + NADPH + H+ + O2 <=> 1-Methylxanthine + NADP+ + formaldehyde + H2O
|
1.13.12
|
–
|
K
|
| |
KEGG:
R07960
|
|
|
|
Caffeine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> paraxanthine + oxidized_[NADPH-hemoprotein_reductase] + formaldehyde + H2O
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
| |
MetaCyc:
RXN66-598
|
|
|
|
paraxanthine + 2 O2 + 2 NADH + 2 H+ <=> xanthine + 2 NAD+ + 2 H2O + 2 formaldehyde
|
1.14.13.128
7-methylxanthine demethylase
|
–
|
|
| |
BRENDA:
BS411138
|
|
|
|
paraxanthine + 2 O2 + 2 NADPH + 2 H+ <=> xanthine + 2 NADP+ + 2 H2O + 2 formaldehyde
|
1.14.13.128
7-methylxanthine demethylase
|
–
|
|
| |
BRENDA:
BS411139
|
|
